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Solution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8

Biosynthesis of the enediyne natural product calicheamicins γ(1) (I) in Micromonospora echinospora ssp. calichensis is initiated by the iterative polyketide synthase (PKS) CalE8. Recent studies showed that CalE8 produces highly conjugated polyenes as potential biosynthetic intermediates and thus bel...

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Detalles Bibliográficos
Autores principales: Lim, Jackwee, Kong, Rong, Murugan, Elavazhagan, Ho, Chun Loong, Liang, Zhao-Xun, Yang, Daiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107222/
https://www.ncbi.nlm.nih.gov/pubmed/21674045
http://dx.doi.org/10.1371/journal.pone.0020549

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