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Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo
BACKGROUND: DC are activated by pathogen-associated molecular patterns (PAMPs), and this is pivotal for the induction of adaptive immune responses. Thereafter, the clearance of activated DC is crucial to prevent immune pathology. While PAMPs are of major interest for vaccine science due to their adj...
Autores principales: | Fuertes Marraco, Silvia A., Scott, Clare L., Bouillet, Philippe, Ives, Annette, Masina, Slavica, Vremec, David, Jansen, Elisa S., O'Reilly, Lorraine A., Schneider, Pascal, Fasel, Nicolas, Shortman, Ken, Strasser, Andreas, Acha-Orbea, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107228/ https://www.ncbi.nlm.nih.gov/pubmed/21674051 http://dx.doi.org/10.1371/journal.pone.0020189 |
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