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Bcl-x(L) Blocks a Mitochondrial Inner Membrane Channel and Prevents Ca(2+) Overload-Mediated Cell Death
Apoptosis is an active process that plays a key role in many physiological and pathological conditions. One of the most important organelles involved in apoptosis regulation is the mitochondrion. An increase in intracellular Ca(2+) is a general mechanism of toxicity in neurons which occurs in respon...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107229/ https://www.ncbi.nlm.nih.gov/pubmed/21674052 http://dx.doi.org/10.1371/journal.pone.0020423 |