Tumor Endothelium Marker-8 Based Decoys Exhibit Superiority over Capillary Morphogenesis Protein-2 Based Decoys as Anthrax Toxin Inhibitors

Anthrax toxin is the major virulence factor produced by Bacillus anthracis. The toxin consists of three protein subunits: protective antigen (PA), lethal factor, and edema factor. Inhibition of PA binding to its receptors, tumor endothelium marker-8 (TEM8) and capillary morphogenesis protein-2 (CMG2...

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Detalles Bibliográficos
Autores principales: Cai, Chenguang, Che, Jinjing, Xu, Long, Guo, Qiang, Kong, Yirong, Fu, Ling, Xu, Junjie, Cheng, Yuanguo, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107238/
https://www.ncbi.nlm.nih.gov/pubmed/21674060
http://dx.doi.org/10.1371/journal.pone.0020646

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