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CD40 Signaling Synergizes with TLR-2 in the BCR Independent Activation of Resting B Cells
Conventionally, signaling through BCR initiates sequence of events necessary for activation and differentiation of B cells. We report an alternative approach, independent of BCR, for stimulating resting B (RB) cells, by involving TLR-2 and CD40 - molecules crucial for innate and adaptive immunity. C...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107243/ https://www.ncbi.nlm.nih.gov/pubmed/21674065 http://dx.doi.org/10.1371/journal.pone.0020651 |