Cargando…
Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams
New gold-catalyzed methods using the β-lactam scaffold have been recently developed for the synthesis of different sized heterocycles. This overview focuses on heterocyclization reactions of allenic and alkynic β-lactams which rely on the activation of the allene and alkyne component. The mechanism...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107458/ https://www.ncbi.nlm.nih.gov/pubmed/21647323 http://dx.doi.org/10.3762/bjoc.7.73 |
| _version_ | 1782205225375891456 |
|---|---|
| author | Alcaide, Benito Almendros, Pedro |
| author_facet | Alcaide, Benito Almendros, Pedro |
| author_sort | Alcaide, Benito |
| collection | PubMed |
| description | New gold-catalyzed methods using the β-lactam scaffold have been recently developed for the synthesis of different sized heterocycles. This overview focuses on heterocyclization reactions of allenic and alkynic β-lactams which rely on the activation of the allene and alkyne component. The mechanism as well as the regio- and stereoselectivity of the cyclizations are also discussed. |
| format | Online Article Text |
| id | pubmed-3107458 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-31074582011-06-06 Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams Alcaide, Benito Almendros, Pedro Beilstein J Org Chem Review New gold-catalyzed methods using the β-lactam scaffold have been recently developed for the synthesis of different sized heterocycles. This overview focuses on heterocyclization reactions of allenic and alkynic β-lactams which rely on the activation of the allene and alkyne component. The mechanism as well as the regio- and stereoselectivity of the cyclizations are also discussed. Beilstein-Institut 2011-05-17 /pmc/articles/PMC3107458/ /pubmed/21647323 http://dx.doi.org/10.3762/bjoc.7.73 Text en Copyright © 2011, Alcaide and Almendros https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Review Alcaide, Benito Almendros, Pedro Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title | Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title_full | Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title_fullStr | Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title_full_unstemmed | Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title_short | Gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| title_sort | gold-catalyzed heterocyclizations in alkynyl- and allenyl-β-lactams |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107458/ https://www.ncbi.nlm.nih.gov/pubmed/21647323 http://dx.doi.org/10.3762/bjoc.7.73 |
| work_keys_str_mv | AT alcaidebenito goldcatalyzedheterocyclizationsinalkynylandallenylblactams AT almendrospedro goldcatalyzedheterocyclizationsinalkynylandallenylblactams |