Mechanism of AMPK Suppression of LXR-dependent Srebp-1c Transcription

Activation of AMP-activated protein kinase (AMPK) inhibits hepatic fatty acid synthesis by suppressing sterol regulatory element-binding protein (SREBP)-1c, a master regulator of hepatic lipogenic gene expression. Using a model cell line rat hepatoma McA-RH7777 (CRL-1601) that mimics the behavior of...

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Detalles Bibliográficos
Autores principales: Yap, Fuichi, Craddock, Lauren, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Short Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107472/
https://www.ncbi.nlm.nih.gov/pubmed/21647332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107472/
https://www.ncbi.nlm.nih.gov/pubmed/21647332

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