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Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux
PURPOSE: To compare echocontrast cystosonography (ECS) using in-vivo agitated saline with fluoroscopic micturating cystourethrography (MCU) in the detection and grading of vesicoureteric reflux (VUR). MATERIALS AND METHODS: This was a prospective study of 25 children, who had MCU between 2007 and 20...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107689/ https://www.ncbi.nlm.nih.gov/pubmed/21655116 http://dx.doi.org/10.2349/biij.7.1.e7 |
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author | Faizah, MZ Kanaheswari, Y Thambidorai, CR Zulfiqar, MA |
author_facet | Faizah, MZ Kanaheswari, Y Thambidorai, CR Zulfiqar, MA |
author_sort | Faizah, MZ |
collection | PubMed |
description | PURPOSE: To compare echocontrast cystosonography (ECS) using in-vivo agitated saline with fluoroscopic micturating cystourethrography (MCU) in the detection and grading of vesicoureteric reflux (VUR). MATERIALS AND METHODS: This was a prospective study of 25 children, who had MCU between 2007 and 2009. ECS was performed and findings documented prior to MCU. Baseline renal and bladder sonograms were obtained. The bladder was filled with normal saline followed by introduction of 10–20 mls of air to generate microbubbles. Detection of VUR was based on two sonographic criteria: (1) presence of microbubbles in the pelvicaliceal system (PCS), and (2) increase in dilatation of the PCS. VUR was graded as (1) Grade I: microbubbles seen in ureter only; (2) Grade II: microbubbles seen in non-dilated PCS; and (3) Grade III-V: microbubbles seen in dilated PCS. The ECS findings were compared using MCU as the gold standard. RESULTS: Of the 50 kidney-ureter (K-U) units studied, ECS detected 9 of 10 K-U units with VUR on MCU. ECS did not detect a Grade II VUR. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value for criterion 1 was 90%, 87.5%, 88%, 64.3% and 97%, respectively, compared to criterion 2 which was 70%, 90%, 86%, 64% and 92%, respectively. The grading of VUR was similar on both ECS and MCU except for one case. CONCLUSION: ECS using agitated saline was a sensitive technique for the detection of VUR. ECS grading was comparable with MCU grading of VUR. |
format | Online Article Text |
id | pubmed-3107689 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia |
record_format | MEDLINE/PubMed |
spelling | pubmed-31076892011-06-08 Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux Faizah, MZ Kanaheswari, Y Thambidorai, CR Zulfiqar, MA Biomed Imaging Interv J Original Article PURPOSE: To compare echocontrast cystosonography (ECS) using in-vivo agitated saline with fluoroscopic micturating cystourethrography (MCU) in the detection and grading of vesicoureteric reflux (VUR). MATERIALS AND METHODS: This was a prospective study of 25 children, who had MCU between 2007 and 2009. ECS was performed and findings documented prior to MCU. Baseline renal and bladder sonograms were obtained. The bladder was filled with normal saline followed by introduction of 10–20 mls of air to generate microbubbles. Detection of VUR was based on two sonographic criteria: (1) presence of microbubbles in the pelvicaliceal system (PCS), and (2) increase in dilatation of the PCS. VUR was graded as (1) Grade I: microbubbles seen in ureter only; (2) Grade II: microbubbles seen in non-dilated PCS; and (3) Grade III-V: microbubbles seen in dilated PCS. The ECS findings were compared using MCU as the gold standard. RESULTS: Of the 50 kidney-ureter (K-U) units studied, ECS detected 9 of 10 K-U units with VUR on MCU. ECS did not detect a Grade II VUR. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value for criterion 1 was 90%, 87.5%, 88%, 64.3% and 97%, respectively, compared to criterion 2 which was 70%, 90%, 86%, 64% and 92%, respectively. The grading of VUR was similar on both ECS and MCU except for one case. CONCLUSION: ECS using agitated saline was a sensitive technique for the detection of VUR. ECS grading was comparable with MCU grading of VUR. Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia 2011-01-01 /pmc/articles/PMC3107689/ /pubmed/21655116 http://dx.doi.org/10.2349/biij.7.1.e7 Text en © 2011 Biomedical Imaging and Intervention Journal http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Faizah, MZ Kanaheswari, Y Thambidorai, CR Zulfiqar, MA Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title | Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title_full | Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title_fullStr | Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title_full_unstemmed | Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title_short | Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
title_sort | echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107689/ https://www.ncbi.nlm.nih.gov/pubmed/21655116 http://dx.doi.org/10.2349/biij.7.1.e7 |
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