Cargando…

Ethical issues posed by cluster randomized trials in health research

The cluster randomized trial (CRT) is used increasingly in knowledge translation research, quality improvement research, community based intervention studies, public health research, and research in developing countries. However, cluster trials raise difficult ethical issues that challenge researche...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weijer, Charles, Grimshaw, Jeremy M, Taljaard, Monica, Binik, Ariella, Boruch, Robert, Brehaut, Jamie C, Donner, Allan, Eccles, Martin P, Gallo, Antonio, McRae, Andrew D, Saginur, Raphael, Zwarenstein, Merrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107798/ https://www.ncbi.nlm.nih.gov/pubmed/21507237 http://dx.doi.org/10.1186/1745-6215-12-100

Ejemplares similares

Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study
por: Taljaard, Monica, et al.
Publicado: (2009)

Does clinical equipoise apply to cluster randomized trials in health research?
por: Binik, Ariella, et al.
Publicado: (2011)

Variability in research ethics review of cluster randomized trials: a scenario-based survey in three countries
por: Taljaard, Monica, et al.
Publicado: (2014)

Who is the research subject in cluster randomized trials in health research?
por: McRae, Andrew D, et al.
Publicado: (2011)

When is informed consent required in cluster randomized trials in health research?
por: McRae, Andrew D, et al.
Publicado: (2011)

What is the role and authority of gatekeepers in cluster randomized trials in health research?
por: Gallo, Antonio, et al.
Publicado: (2012)

Researchers’ perceptions of ethical challenges in cluster randomized trials: a qualitative analysis
por: McRae, Andrew D, et al.
Publicado: (2013)

Inadequate reporting of research ethics review and informed consent in cluster randomised trials: review of random sample of published trials
por: Taljaard, Monica, et al.
Publicado: (2011)

The Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials
por: Weijer, Charles, et al.
Publicado: (2012)

Impact of CONSORT extension for cluster randomised trials on quality of reporting and study methodology: review of random sample of 300 trials, 2000-8
por: Ivers, N M, et al.
Publicado: (2011)

Electronic search strategies to identify reports of cluster randomized trials in MEDLINE: low precision will improve with adherence to reporting standards
por: Taljaard, Monica, et al.
Publicado: (2010)

Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation
por: Goldstein, Cory E., et al.
Publicado: (2018)

Patient Partner Perspectives Regarding Ethically and Clinically Important Aspects of Trial Design in Pragmatic Cluster Randomized Trials for Hemodialysis
por: Nicholls, Stuart G., et al.
Publicado: (2021)

Stakeholder views regarding ethical issues in the design and conduct of pragmatic trials: study protocol
por: Nicholls, Stuart G., et al.
Publicado: (2018)

The ethical challenges raised in the design and conduct of pragmatic trials: an interview study with key stakeholders
por: Nicholls, Stuart G., et al.
Publicado: (2019)

Ethical Issues in the Design and Conduct of Pragmatic Cluster Randomized Trials in Hemodialysis Care: An Interview Study With Key Stakeholders
por: Nicholls, Stuart G., et al.
Publicado: (2020)

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review
por: Nicholls, Stuart G., et al.
Publicado: (2015)

Accommodating quality and service improvement research within existing ethical principles
por: Goldstein, Cory E., et al.
Publicado: (2018)

Mail merge can be used to create personalized questionnaires in complex surveys
por: Taljaard, Monica, et al.
Publicado: (2015)

Reporting of key methodological and ethical aspects of cluster trials in hemodialysis require improvement: a systematic review
por: Al-Jaishi, Ahmed A., et al.
Publicado: (2020)

Ethical issues in implementation research: a discussion of the problems in achieving informed consent
por: Hutton, Jane L, et al.
Publicado: (2008)

When and how should we cluster and cross over: methodological and ethical issues
por: Goldstein, Cory E., et al.
Publicado: (2018)

Heterogeneity in pragmatic randomised trials: sources and management
por: Giraudeau, Bruno, et al.
Publicado: (2022)

Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol
por: Taljaard, Monica, et al.
Publicado: (2018)

SARS-CoV-2 challenge studies: ethics and risk minimisation
por: Bull, Susan, et al.
Publicado: (2021)

Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): Protocol for a pragmatic, cluster-randomized controlled trial
por: Ivers, Noah M, et al.
Publicado: (2012)

Theory of planned behaviour can help understand processes underlying the use of two emergency medicine diagnostic imaging rules
por: Perez, Richard, et al.
Publicado: (2014)

TwiC or treat? Are trials within cohorts ethically defensible?
por: Weijer, Charles, et al.
Publicado: (2017)

Informed consent in cluster randomised trials: a guide for the perplexed
por: Nix, Hayden P, et al.
Publicado: (2021)

Requirements for ethics committee review for studies submitted to Implementation Science
por: Eccles, Martin P, et al.
Publicado: (2011)

Changing patient preferences toward better trial recruitment: an ethical analysis
por: Al, Pepijn, et al.
Publicado: (2023)

Can patient decision aids help people make good decisions about participating in clinical trials? A study protocol
por: Brehaut, Jamie C, et al.
Publicado: (2008)

Educational outreach to general practitioners reduces children's asthma symptoms: a cluster randomised controlled trial
por: Zwarenstein, Merrick, et al.
Publicado: (2007)

A Defense of The-Risks-of-Daily-Life
por: Binik, Ariella
Publicado: (2017)

Does benefit justify research with children?
por: Binik, Ariella
Publicado: (2017)

Response to Merz
por: Al, Pepijn, et al.
Publicado: (2023)

Ethical implications of excessive cluster sizes in cluster randomised trials
por: Hemming, Karla, et al.
Publicado: (2018)

Testing a TheoRY-inspired MEssage ('TRY-ME'): a sub-trial within the Ontario Printed Educational Message (OPEM) trial
por: Francis, Jillian J, et al.
Publicado: (2007)

Ethical issues raised by cluster randomised trials conducted in low-resource settings: identifying gaps in the Ottawa Statement through an analysis of the PURE Malawi trial
por: Mtande, Tiwonge K, et al.
Publicado: (2019)

Specific challenges posed by artificial intelligence in research ethics
por: Bouhouita-Guermech, Sarah, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cniue6nvl22cto0gut3sovcinm