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Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning

Previous studies on mice with a disruption of the gene encoding acid-sensing ion channel 1a (ASIC1a) suggest that ASIC1a is required for normal fear behavior. To investigate the effects of altering the subunit composition of brain ASICs on behavior, we developed transgenic mice expressing ASIC3 via...

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Detalles Bibliográficos
Autores principales:	Vralsted, V C, Price, M P, Du, J, Schnizler, M, Wunsch, A M, Ziemann, A E, Welsh, M J, Wemmie, J A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107921/ https://www.ncbi.nlm.nih.gov/pubmed/21324060 http://dx.doi.org/10.1111/j.1601-183X.2011.00683.x

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