Cargando…

Gatifloxacin versus chloramphenicol for uncomplicated enteric fever: an open-label, randomised, controlled trial

BACKGROUND: We aimed to investigate whether gatifloxacin, a new generation and affordable fluoroquinolone, is better than chloramphenicol for the treatment of uncomplicated enteric fever in children and adults. METHODS: We did an open-label randomised superiority trial at Patan Hospital, Kathmandu,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arjyal, Amit, Basnyat, Buddha, Koirala, Samir, Karkey, Abhilasha, Dongol, Sabina, Agrawaal, Krishna Kumar, Shakya, Nikki, Shrestha, Kabina, Sharma, Manish, Lama, Sanju, Shrestha, Kasturi, Khatri, Nely Shrestha, Shrestha, Umesh, Campbell, James I, Baker, Stephen, Farrar, Jeremy, Wolbers, Marcel, Dolecek, Christiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science ;, The Lancet Pub. Group 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108101/ https://www.ncbi.nlm.nih.gov/pubmed/21531174 http://dx.doi.org/10.1016/S1473-3099(11)70089-5

Ejemplares similares

Gatifloxacin Versus Ofloxacin for the Treatment of Uncomplicated Enteric Fever in Nepal: An Open-Label, Randomized, Controlled Trial
por: Koirala, Samir, et al.
Publicado: (2013)

Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial
por: Arjyal, Amit, et al.
Publicado: (2016)

An Open Randomized Comparison of Gatifloxacin versus Cefixime for the Treatment of Uncomplicated Enteric Fever
por: Pandit, Anil, et al.
Publicado: (2007)

The Microbiological and Clinical Characteristics of Invasive Salmonella in Gallbladders from Cholecystectomy Patients in Kathmandu, Nepal
por: Dongol, Sabina, et al.
Publicado: (2012)

The Application of GeneXpert MTB/RIF for Smear-Negative TB Diagnosis as a Fee-Paying Service at a South Asian General Hospital
por: Shrestha, Poojan, et al.
Publicado: (2015)

Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal
por: Thompson, Corinne N., et al.
Publicado: (2017)

Perspectives of pharmacy employees on an inappropriate use of antimicrobials in Kathmandu, Nepal
por: Shrestha, Nistha, et al.
Publicado: (2023)

Aetiologies of Central Nervous System infections in adults in Kathmandu, Nepal: A prospective hospital-based study
por: Giri, Abhishek, et al.
Publicado: (2013)

A 23-year retrospective investigation of Salmonella Typhi and Salmonella Paratyphi isolated in a tertiary Kathmandu hospital
por: Zellweger, Raphaël M., et al.
Publicado: (2017)

Undifferentiated Febrile Illness in Kathmandu, Nepal
por: Thompson, Corinne N., et al.
Publicado: (2015)

Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal
por: Darton, Thomas C., et al.
Publicado: (2017)

Outbreaks of Serratia marcescens and Serratia rubidaea bacteremia in a central Kathmandu hospital following the 2015 earthquakes
por: Karkey, Abhilasha, et al.
Publicado: (2018)

Evaluation of an Electricity-free, Culture-based Approach for Detecting Typhoidal Salmonella Bacteremia during Enteric Fever in a High Burden, Resource-limited Setting
por: Andrews, Jason R., et al.
Publicado: (2013)

Co-trimoxazole versus azithromycin for the treatment of undifferentiated febrile illness in Nepal: study protocol for a randomized controlled trial
por: Pokharel, Sunil, et al.
Publicado: (2017)

Differential Epidemiology of Salmonella Typhi and Paratyphi A in Kathmandu, Nepal: A Matched Case Control Investigation in a Highly Endemic Enteric Fever Setting
por: Karkey, Abhilasha, et al.
Publicado: (2013)

Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission
por: Baker, Stephen, et al.
Publicado: (2011)

The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens
por: Nga, Tran Vu Thieu, et al.
Publicado: (2010)

The impact of migration and antimicrobial resistance on the transmission dynamics of typhoid fever in Kathmandu, Nepal: A mathematical modelling study
por: Saad, Neil J., et al.
Publicado: (2017)

Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial
por: Theiss-Nyland, Katherine, et al.
Publicado: (2019)

Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever
por: Näsström, Elin, et al.
Publicado: (2014)

Changing Antimicrobial Resistance Trends in Kathmandu, Nepal: A 23-Year Retrospective Analysis of Bacteraemia
por: Zellweger, Raphaël M., et al.
Publicado: (2018)

Direct inference and control of genetic population structure from RNA sequencing data
por: Fachrul, Muhamad, et al.
Publicado: (2023)

A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure
por: Pham Thanh, Duy, et al.
Publicado: (2016)

The Burden and Characteristics of Enteric Fever at a Healthcare Facility in a Densely Populated Area of Kathmandu
por: Karkey, Abhilasha, et al.
Publicado: (2010)

High altitude pulmonary edema (HAPE) in a Himalayan trekker: a case report
por: Shrestha, Promish, et al.
Publicado: (2014)

A Multi-Center Randomised Controlled Trial of Gatifloxacin versus Azithromycin for the Treatment of Uncomplicated Typhoid Fever in Children and Adults in Vietnam
por: Dolecek, Christiane, et al.
Publicado: (2008)

Logistics of Implementing a Large-scale Typhoid Vaccine Trial in Kathmandu, Nepal
por: Colin-Jones, Rachel, et al.
Publicado: (2019)

Epidemiology, etiology, and diagnosis of health care acquired pneumonia including ventilator-associated pneumonia in Nepal
por: Dongol, Sabina, et al.
Publicado: (2021)

Azithromycin and cefixime combination versus azithromycin alone for the out-patient treatment of clinically suspected or confirmed uncomplicated typhoid fever in South Asia: a randomised controlled trial protocol
por: Giri, Abhishek, et al.
Publicado: (2021)

Risk factors for the development of neonatal sepsis in a neonatal intensive care unit of a tertiary care hospital of Nepal
por: Manandhar, Sulochana, et al.
Publicado: (2021)

A Rapid, Multiplexed, High-Throughput Flow-Through Membrane Immunoassay: A Convenient Alternative to ELISA
por: Ramachandran, Sujatha, et al.
Publicado: (2013)

Langerhans cell histiocytosis in a pediatric patient: A typical presentation with oral manifestations
por: Shakya, Royasa, et al.
Publicado: (2023)

Trimethoprim-sulfamethoxazole Versus Azithromycin for the Treatment of Undifferentiated Febrile Illness in Nepal: A Double-blind, Randomized, Placebo-controlled Trial
por: Giri, Abhishek, et al.
Publicado: (2020)

A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes
por: Manandhar, Sulochana, et al.
Publicado: (2020)

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases
por: Blohmke, Christoph J, et al.
Publicado: (2019)

Melioidosis: misdiagnosed in Nepal
por: Shrestha, Neha, et al.
Publicado: (2019)

Genomic epidemiology, antimicrobial resistance and virulence factors of Enterobacter cloacae complex causing potential community-onset bloodstream infections in a tertiary care hospital of Nepal
por: Manandhar, Sulochana, et al.
Publicado: (2022)

Efficacy of Typhoid Conjugate Vaccine in Nepal: An Interim Analysis of a Participant-and Observer-Blinded Randomized Phase III Trial
por: Shakya, Mila, et al.
Publicado: (2019)

Diagnostic metabolite biomarkers of chronic typhoid carriage
por: Näsström, Elin, et al.
Publicado: (2018)

Conducting Randomized Controlled Trials for the Treatment of Enteric Fever
por: Shrestha, Poojan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ihf4gp948rce3q9nd5lpae46td