Cargando…

Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death

BACKGROUND: Silibinin, a natural polyphenolic flavonoid, has been reported to induce cell death in various cancer cell types. However, the molecular mechanism is not clearly defined. Our previous study showed that silibinin induces glioma cell death and its effect was effectively prevented by calpai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Ji C, Shin, Won Y, Kim, Thae H, Kwon, Chae H, Kim, Jae H, Kim, Yong K, Kim, Ki H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108340/ https://www.ncbi.nlm.nih.gov/pubmed/21501525 http://dx.doi.org/10.1186/1756-9966-30-44

Ejemplares similares

Autophagy activated by silibinin contributes to glioma cell death via induction of oxidative stress-mediated BNIP3-dependent nuclear translocation of AIF
por: Wang, Chongcheng, et al.
Publicado: (2020)

Proteomic Analysis between U87MG and U343MG-A Cell Lines: Searching for Candidate Proteins for Glioma Invasion
por: Pei, Jian, et al.
Publicado: (2014)

Exercise-induced sudden cardiac death is caused by mitochondrio-nuclear translocation of AIF
por: Abdellatif, Mahmoud, et al.
Publicado: (2021)

Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells
por: Sukumari-Ramesh, Sangeetha, et al.
Publicado: (2015)

Suppressing H19 Modulates Tumorigenicity and Stemness in U251 and U87MG Glioma Cells
por: Li, Weiguo, et al.
Publicado: (2016)

LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells
por: Laurentino, Talita de S., et al.
Publicado: (2021)

Exosome Proteome of U-87MG Glioblastoma Cells
por: Chun, Sohyun, et al.
Publicado: (2016)

Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells
por: Bernhart, Eva, et al.
Publicado: (2015)

Dimethyl celecoxib sensitizes gastric cancer cells to ABT‐737 via AIF nuclear translocation
por: Zhang, Bo, et al.
Publicado: (2016)

Bacitracin Inhibits the Migration of U87-MG Glioma Cells via Interferences of the Integrin Outside-in Signaling Pathway
por: Li, Songyuan, et al.
Publicado: (2016)

Metallothinein 1E Enhances Glioma Invasion through Modulation Matrix Metalloproteinases-2 and 9 in U87MG Mouse Brain Tumor Model
por: Hur, Hyuk, et al.
Publicado: (2016)

Anti-Proliferative Potential of Quercetin Loaded Polymeric Mixed Micelles on Rat C6 and Human U87MG Glioma Cells
por: Paranthaman, Sathishbabu, et al.
Publicado: (2022)

Insights from the Molecular Modelling and Docking Analysis of AIF-NLS complex to infer Nuclear Translocation of the Protein
por: Srivaths, Akash, et al.
Publicado: (2018)

PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis
por: Xing, Yao, et al.
Publicado: (2021)

Survivin-specific small interfering RNAs enhance sensitivity of glioma U-87MG cells to paclitaxel by promoting apoptosis☆
por: Xie, Yunliang, et al.
Publicado: (2012)

Solid Lipid Nanoparticles of Albendazole for Enhancing Cellular Uptake and Cytotoxicity against U-87 MG Glioma Cell Lines
por: Marslin, Gregory, et al.
Publicado: (2017)

Combination of Caffeic Acid Phenethyl Ester and Crocin Realign Potential Molecular Markers in U87-MG Glioma Cells
por: Mir, Ashaq Hussain, et al.
Publicado: (2023)

Inhibitor of differentiation 1 in U87MG glioblastoma cells promotes HUVEC sprouting through endothelin-1
por: Choi, Sang-Hun, et al.
Publicado: (2022)

Propolis changes the anticancer activity of temozolomide in U87MG human glioblastoma cell line
por: Markiewicz-Żukowska, Renata, et al.
Publicado: (2013)

Calpain: a molecule to induce AIF-mediated necroptosis in RGC-5 following elevated hydrostatic pressure
por: Shang, Lei, et al.
Publicado: (2014)

Efficacy and Safety of Human Serum Albumin–Cisplatin Complex in U87MG Xenograft Mouse Models
por: Park, Cho Rong, et al.
Publicado: (2020)

Cyclophilin D Regulates the Nuclear Translocation of AIF, Cardiac Endothelial Cell Necroptosis and Murine Cardiac Transplant Injury
por: Qamar, Adnan, et al.
Publicado: (2021)

Mitochondria Transcription Factor A: A Putative Target for the Effect of Melatonin on U87MG Malignant Glioma Cell Line
por: Franco, Daiane G., et al.
Publicado: (2018)

Decorin‐mediated inhibition of the migration of U87MG glioma cells involves activation of autophagy and suppression of TGF‐β signaling
por: Yao, Ting, et al.
Publicado: (2016)

IDH1-R132H mutation radiosensitizes U87MG glioma cells via epigenetic downregulation of TIGAR
por: Yin, Narui, et al.
Publicado: (2020)

Pharmacological Inhibition of Membrane Signaling Mechanisms Reduces the Invasiveness of U87-MG and U251-MG Glioblastoma Cells In Vitro
por: Varricchio, Alanah, et al.
Publicado: (2023)

Effect of eflornithine on mutation frequency in temozolomide-treated U87MG cells
por: Yam, Noymi, et al.
Publicado: (2020)

Chemosensitization of U-87 MG Glioblastoma Cells by Neobavaisoflavone towards Doxorubicin and Etoposide
por: Maszczyk, Mateusz, et al.
Publicado: (2022)

Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells
por: Gjika, Eda, et al.
Publicado: (2020)

TAX1BP1 contributes to deoxypodophyllotoxin-induced glioma cell parthanatos via inducing nuclear translocation of AIF by activation of mitochondrial respiratory chain complex I
por: Wang, Xuan-zhong, et al.
Publicado: (2023)

The effect of downregulation of Stathmin gene on biological behaviors of U373 and U87-MG glioblastoma cells
por: Liu, Ping, et al.
Publicado: (2018)

Metabolic Impact of Anti-Angiogenic Agents on U87 Glioma Cells
por: Mesti, Tanja, et al.
Publicado: (2014)

All-trans retinoic acid therapy induces asymmetric division of glioma stem cells from the U87MG cell line
por: Wang, Ruizhi, et al.
Publicado: (2019)

OTUD1 Activates Caspase‐Independent and Caspase‐Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation
por: Luo, Qingyu, et al.
Publicado: (2021)

Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR
por: Bassi, Rosaria, et al.
Publicado: (2023)

Atomoxetine and Fluoxetine Activate AMPK-ACC-CPT1 Pathway in Human SH-SY5Y and U-87 MG Cells
por: Jeon, Songhee, et al.
Publicado: (2023)

Sulforaphane Inhibits Invasion via Activating ERK1/2 Signaling in Human Glioblastoma U87MG and U373MG Cells
por: Li, Chunliu, et al.
Publicado: (2014)

Suppression of matrix metalloproteinase-2-mediated cell invasion in U87MG, human glioma cells by anti-microtubule agent: in vitro study.
por: Yoshida, D., et al.
Publicado: (1998)

Evaluation of Tumor Regulatory Genes and Apoptotic Pathways in The Cytotoxic Effect of Cytochalasin H on Malignant Human Glioma Cell Line (U87MG)
por: Heidarzadeh, Samaneh, et al.
Publicado: (2019)

Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics
por: Indira Chandran, Vineesh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_toqtc9v6prbd47b8c0d6im55us