Mice Lacking NKT Cells but with a Complete Complement of CD8(+) T-Cells Are Not Protected against the Metabolic Abnormalities of Diet-Induced Obesity

The contribution of natural killer T (NKT) cells to the pathogenesis of metabolic abnormalities of obesity is controversial. While the combined genetic deletion of NKT and CD8(+) T-cells improves glucose tolerance and reduces inflammation, interpretation of these data have been complicated by the re...

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Detalles Bibliográficos
Autores principales: Mantell, Benjamin S., Stefanovic-Racic, Maja, Yang, Xiao, Dedousis, Nikolas, Sipula, Ian J., O'Doherty, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108591/
https://www.ncbi.nlm.nih.gov/pubmed/21674035
http://dx.doi.org/10.1371/journal.pone.0019831

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