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Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo

The acylphloroglucinol hyperforin (Hyp) from St. John's wort possesses anti-inflammatory and anti-carcinogenic properties which were ascribed among others to the inhibition of 5-lipoxygenase. Here, we investigated whether Hyp also interferes with prostanoid generation in biological systems, par...

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Detalles Bibliográficos
Autores principales:	Koeberle, Andreas, Rossi, Antonietta, Bauer, Julia, Dehm, Friederike, Verotta, Luisella, Northoff, Hinnak, Sautebin, Lidia, Werz, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108608/ https://www.ncbi.nlm.nih.gov/pubmed/21687502 http://dx.doi.org/10.3389/fphar.2011.00007

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