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Effects of casoxin 4 on morphine inhibition of small animal intestinal contractility and gut transit in the mouse

BACKGROUND AND AIMS: Chronic opioid analgesia has the debilitating side-effect of constipation in human patients. The major aims of this study were to: 1) characterize the opioid-specific antagonism of morphine-induced inhibition of electrically driven contraction of the small intestine of mice, rat...

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Detalles Bibliográficos
Autores principales: Patten, Glen S, Head, Richard J, Abeywardena, Mahinda Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108675/
https://www.ncbi.nlm.nih.gov/pubmed/21694869
http://dx.doi.org/10.2147/CEG.S16161