WFDC1 expression identifies memory CD4 T- lymphocytes rendered vulnerable to cell-cell HIV-1 transfer by promoting intercellular adhesive junctions

BACKGROUND: Elucidating mechanisms that promote HIV-1 transfer between CD4(+ )T-lymphocytes and their subsequent loss is of importance to HIV-1 pathogenesis. We recently reported that whey acidic protein, ps20, promotes cell-free HIV-1 spread through ICAM-1 modulation. Since ICAM-1 is pivotal in cel...

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Detalles Bibliográficos
Autores principales: Alvarez, Raymond A, Thorborn, Georgina, Reading, James L, Reddy, Shalini Kamu, Vyakarnam, Annapurna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108927/
https://www.ncbi.nlm.nih.gov/pubmed/21545747
http://dx.doi.org/10.1186/1742-4690-8-29

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