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Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease
3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger, provides neuroprotection in stroke models and patients. In this study, we investigated its neuroprotective effects in a chronic rotenone rat model for Parkinson's disease. Here we showed that a five-week treat...
Autores principales: | Xiong, Nian, Xiong, Jing, Khare, Ghanshyam, Chen, Chunnuan, Huang, Jinsha, Zhao, Ying, Zhang, Zhentao, Qiao, Xian, Feng, Yuan, Reesaul, Harrish, Zhang, Yongxue, Sun, Shenggang, Lin, Zhicheng, Wang, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108992/ https://www.ncbi.nlm.nih.gov/pubmed/21677777 http://dx.doi.org/10.1371/journal.pone.0020677 |
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