NGF and proNGF Regulate Functionally Distinct mRNAs in PC12 Cells: An Early Gene Expression Profiling

The biological activities of NGF and of its precursor proNGF are quite distinct, due to different receptor binding profiles, but little is known about how proNGF regulates gene expression. Whether proNGF is a purely pro-apoptotic molecule and/or simply a “less potent NGF” is still a matter of debate...

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Detalles Bibliográficos
Autores principales: D'Onofrio, Mara, Paoletti, Francesca, Arisi, Ivan, Brandi, Rossella, Malerba, Francesca, Fasulo, Luisa, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109000/
https://www.ncbi.nlm.nih.gov/pubmed/21677785
http://dx.doi.org/10.1371/journal.pone.0020839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109000/
https://www.ncbi.nlm.nih.gov/pubmed/21677785
http://dx.doi.org/10.1371/journal.pone.0020839

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