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DNA Nuclear Targeting Sequences for Non-Viral Gene Delivery

PURPOSE: To evaluate if introduction of DNA nuclear Targeting Sequences (DTS; i.e. recognition sequences for endogenous DNA-binding proteins) in plasmid DNA (pDNA) leads to increased transfection efficiency of non-viral gene delivery by virtue of enhanced nuclear import of the pDNA. METHODS: A set o...

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Detalles Bibliográficos
Autores principales:	van Gaal, Ethlinn V. B., Oosting, Ronald S., van Eijk, Roel, Bakowska, Marta, Feyen, Dries, Kok, Robbert Jan, Hennink, Wim E., Crommelin, Daan J. A., Mastrobattista, Enrico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2011
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109246/ https://www.ncbi.nlm.nih.gov/pubmed/21424159 http://dx.doi.org/10.1007/s11095-011-0407-8

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