Structural basis of fumarate hydratase deficiency

Fumarate hydratase catalyzes the stereospecific hydration across the olefinic double bond in fumarate leading to L-malate. The enzyme is expressed in mitochondrial and cytosolic compartments, and participates in the Krebs cycle in mitochondria, as well as in regulation of cytosolic fumarate levels....

Descripción completa

Detalles Bibliográficos
Autores principales: Picaud, Sarah, Kavanagh, Kathryn L., Yue, Wyatt W., Lee, Wen Hwa, Muller-Knapp, Susanne, Gileadi, Opher, Sacchettini, James, Oppermann, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109261/
https://www.ncbi.nlm.nih.gov/pubmed/21445611
http://dx.doi.org/10.1007/s10545-011-9294-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109261/
https://www.ncbi.nlm.nih.gov/pubmed/21445611
http://dx.doi.org/10.1007/s10545-011-9294-8

Ejemplares similares