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Heparanase isoform expression and extracellular matrix remodeling in intervertebral disc degenerative disease

OBJECTIVE: To determine the molecules involved in extracellular matrix remodeling and to identify and quantify heparanase isoforms present in herniated and degenerative discs. INTRODUCTION: Heparanase is an endo-beta-glucuronidase that specifically acts upon the heparan sulfate chains of proteoglyca...

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Detalles Bibliográficos
Autores principales: Rodrigues, Luciano Miller Reis, Theodoro, Thérèse Rachell, Matos, Leandro Luongo, Mader, Ana Maria, Milani, Carlo, da Silva Pinhal, Maria Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109393/
https://www.ncbi.nlm.nih.gov/pubmed/21789398
http://dx.doi.org/10.1590/S1807-59322011000500030