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Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial
BACKGROUND: Elderly and frail patients with cancer, although often treated with chemotherapy, are under-represented in clinical trials. We designed FOCUS2 to investigate reduced-dose chemotherapy options and to seek objective predictors of outcome in frail patients with advanced colorectal cancer. M...
Autores principales: | Seymour, Matthew T, Thompson, Lindsay C, Wasan, Harpreet S, Middleton, Gary, Brewster, Alison E, Shepherd, Stephen F, O'Mahony, M Sinead, Maughan, Timothy S, Parmar, Mahesh, Langley, Ruth E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lancet Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109515/ https://www.ncbi.nlm.nih.gov/pubmed/21570111 http://dx.doi.org/10.1016/S0140-6736(11)60399-1 |
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