Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection

During the spring of 2009, a new influenza A (H1N1) virus of swine origin emerged and spread worldwide causing a pandemic influenza. Here, 329 naso-pharyngeal swabs collected from patients with flu-like symptoms were analyzed by real-time PCR for the presence of H1N1 2009 pandemic virus. Twenty-five...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciccozzi, Massimo, Babakir-Mina, Muhammed, Lo Presti, Alessandra, Marcuccilli, Fabbio, Perno, Carlo Federico, Ciotti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109524/
https://www.ncbi.nlm.nih.gov/pubmed/21660186
http://dx.doi.org/10.2174/1874357901105010022
_version_ 1782205442102919168
author Ciccozzi, Massimo
Babakir-Mina, Muhammed
Lo Presti, Alessandra
Marcuccilli, Fabbio
Perno, Carlo Federico
Ciotti, Marco
author_facet Ciccozzi, Massimo
Babakir-Mina, Muhammed
Lo Presti, Alessandra
Marcuccilli, Fabbio
Perno, Carlo Federico
Ciotti, Marco
author_sort Ciccozzi, Massimo
collection PubMed
description During the spring of 2009, a new influenza A (H1N1) virus of swine origin emerged and spread worldwide causing a pandemic influenza. Here, 329 naso-pharyngeal swabs collected from patients with flu-like symptoms were analyzed by real-time PCR for the presence of H1N1 2009 pandemic virus. Twenty-five samples collected from immunocompetent and immunodepressed patients contained the H1N1 pandemic virus. Phylogenetic analysis of the hemagglutinin and neuraminidase genes showed no obvious differences in terms of similarity and/or homology between the sequences identified in immunocompetent individuals and those obtained from immunocompromised patients. Pre-existing clinical conditions may influence the outcome of H1N1 disease.
format Online
Article
Text
id pubmed-3109524
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Bentham Open
record_format MEDLINE/PubMed
spelling pubmed-31095242011-06-09 Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection Ciccozzi, Massimo Babakir-Mina, Muhammed Lo Presti, Alessandra Marcuccilli, Fabbio Perno, Carlo Federico Ciotti, Marco Open Virol J Article During the spring of 2009, a new influenza A (H1N1) virus of swine origin emerged and spread worldwide causing a pandemic influenza. Here, 329 naso-pharyngeal swabs collected from patients with flu-like symptoms were analyzed by real-time PCR for the presence of H1N1 2009 pandemic virus. Twenty-five samples collected from immunocompetent and immunodepressed patients contained the H1N1 pandemic virus. Phylogenetic analysis of the hemagglutinin and neuraminidase genes showed no obvious differences in terms of similarity and/or homology between the sequences identified in immunocompetent individuals and those obtained from immunocompromised patients. Pre-existing clinical conditions may influence the outcome of H1N1 disease. Bentham Open 2011-04-07 /pmc/articles/PMC3109524/ /pubmed/21660186 http://dx.doi.org/10.2174/1874357901105010022 Text en © Ciccozzi et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http: //creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Ciccozzi, Massimo
Babakir-Mina, Muhammed
Lo Presti, Alessandra
Marcuccilli, Fabbio
Perno, Carlo Federico
Ciotti, Marco
Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title_full Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title_fullStr Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title_full_unstemmed Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title_short Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
title_sort phylogenesis and clinical aspects of pandemic 2009 influenza a (h1n1) virus infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109524/
https://www.ncbi.nlm.nih.gov/pubmed/21660186
http://dx.doi.org/10.2174/1874357901105010022
work_keys_str_mv AT ciccozzimassimo phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection
AT babakirminamuhammed phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection
AT loprestialessandra phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection
AT marcuccillifabbio phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection
AT pernocarlofederico phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection
AT ciottimarco phylogenesisandclinicalaspectsofpandemic2009influenzaah1n1virusinfection

Ejemplares similares