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Quantification and Evaluation of the Role of Antielastin Autoantibodies in the Emphysematous Lung

Chronic obstructive pulmonary disease (COPD) may be an autoimmune disease. Smoking causes an imbalance of proteases and antiproteases in the lung resulting in the generation of elastin peptides that can potentially act as autoantigens. Similar to COPD, Z alpha-1 antitrypsin deficiency (Z-A1ATD) and...

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Detalles Bibliográficos
Autores principales: Low, Teck Boon, Greene, Catherine M., O'Neill, Shane J., McElvaney, Noel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109555/
https://www.ncbi.nlm.nih.gov/pubmed/21660246
http://dx.doi.org/10.1155/2011/826160