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Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
Aberrant activation of a latent embryonic program - known as the epithelial-mesenchymal transition (EMT) - can endow cancer cells with the migratory and invasive capabilities associated with metastatic competence. The induction of EMT entails the loss of epithelial characteristics and the de novo ac...
Autores principales: | May, Caitlin D, Sphyris, Nathalie, Evans, Kurt W, Werden, Steven J, Guo, Wenjun, Mani, Sendurai A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109556/ https://www.ncbi.nlm.nih.gov/pubmed/21392411 http://dx.doi.org/10.1186/bcr2789 |
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