p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients

INTRODUCTION: Normal function of the p53 network is lost in most cancers, often through p53 mutation. The clinical impact of p53 mutations in breast cancer remains uncertain, especially where p53 isoforms may modify the effects of these p53 mutations. METHODS: Expression of p53β and p53γ isoforms, t...

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Detalles Bibliográficos
Autores principales: Bourdon, Jean-Christophe, Khoury, Marie P, Diot, Alexandra, Baker, Lee, Fernandes, Kenneth, Aoubala, Mustapha, Quinlan, Philip, Purdie, Colin A, Jordan, Lee B, Prats, Anne-Catherine, Lane, David P, Thompson, Alastair M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109573/
https://www.ncbi.nlm.nih.gov/pubmed/21251329
http://dx.doi.org/10.1186/bcr2811

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