Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals

INTRODUCTION: Two major high-penetrance breast cancer genes, BRCA1 and BRCA2, are responsible for approximately 20% of hereditary breast cancer (HBC) cases in Finland. Additionally, rare mutations in several other genes that interact with BRCA1 and BRCA2 increase the risk of HBC. Still, a majority o...

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Detalles Bibliográficos
Autores principales: Kuusisto, Kirsi M, Bebel, Aleksandra, Vihinen, Mauno, Schleutker, Johanna, Sallinen, Satu-Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109589/
https://www.ncbi.nlm.nih.gov/pubmed/21356067
http://dx.doi.org/10.1186/bcr2832

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