Model Systems to Study Plague Pathogenesis and Develop New Therapeutics

The Gram negative bacterium Yersinia pestis can infect humans by multiple routes to cause plague. Three plague pandemics have occurred and Y. pestis has been linked to biowarfare in the past. The continued risk of plague as a bioweapon has prompted increased research to understand Y. pestis pathogen...

Descripción completa

Detalles Bibliográficos
Autor principal: Lawrenz, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109633/
https://www.ncbi.nlm.nih.gov/pubmed/21687720
http://dx.doi.org/10.3389/fmicb.2010.00119
_version_ 1782205454828437504
author Lawrenz, Matthew B.
author_facet Lawrenz, Matthew B.
author_sort Lawrenz, Matthew B.
collection PubMed
description The Gram negative bacterium Yersinia pestis can infect humans by multiple routes to cause plague. Three plague pandemics have occurred and Y. pestis has been linked to biowarfare in the past. The continued risk of plague as a bioweapon has prompted increased research to understand Y. pestis pathogenesis and develop new plague therapeutics. Several in vivo models have been developed for this research and are reviewed here.
format Online
Article
Text
id pubmed-3109633
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Frontiers Research Foundation
record_format MEDLINE/PubMed
spelling pubmed-31096332011-06-16 Model Systems to Study Plague Pathogenesis and Develop New Therapeutics Lawrenz, Matthew B. Front Microbiol Microbiology The Gram negative bacterium Yersinia pestis can infect humans by multiple routes to cause plague. Three plague pandemics have occurred and Y. pestis has been linked to biowarfare in the past. The continued risk of plague as a bioweapon has prompted increased research to understand Y. pestis pathogenesis and develop new plague therapeutics. Several in vivo models have been developed for this research and are reviewed here. Frontiers Research Foundation 2010-11-04 /pmc/articles/PMC3109633/ /pubmed/21687720 http://dx.doi.org/10.3389/fmicb.2010.00119 Text en Copyright © 2010 Lawrenz. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Microbiology
Lawrenz, Matthew B.
Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title_full Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title_fullStr Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title_full_unstemmed Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title_short Model Systems to Study Plague Pathogenesis and Develop New Therapeutics
title_sort model systems to study plague pathogenesis and develop new therapeutics
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109633/
https://www.ncbi.nlm.nih.gov/pubmed/21687720
http://dx.doi.org/10.3389/fmicb.2010.00119
work_keys_str_mv AT lawrenzmatthewb modelsystemstostudyplaguepathogenesisanddevelopnewtherapeutics

Ejemplares similares