Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis

Direct hemoperfusion using polymyxin B–immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic t...

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Detalles Bibliográficos
Autores principales: Malleshappa, P., Ranganath, R., Chaudhari, A. P., Singhai, P., Aghariya, M., Shah, A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109782/
https://www.ncbi.nlm.nih.gov/pubmed/21655169
http://dx.doi.org/10.4103/0971-4065.78077
Descripción
Sumario:Direct hemoperfusion using polymyxin B–immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India.

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