Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells

BACKGROUND: Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have indicated that activation of protein kinase C (PKC) ca...

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Detalles Bibliográficos
Autores principales: Wen, Jie, Ribeiro, Rachel, Zhang, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110130/
https://www.ncbi.nlm.nih.gov/pubmed/21510893
http://dx.doi.org/10.1186/1742-2094-8-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110130/
https://www.ncbi.nlm.nih.gov/pubmed/21510893
http://dx.doi.org/10.1186/1742-2094-8-38

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