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Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells

BACKGROUND: Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have indicated that activation of protein kinase C (PKC) ca...

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Detalles Bibliográficos
Autores principales:	Wen, Jie, Ribeiro, Rachel, Zhang, Yumin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110130/ https://www.ncbi.nlm.nih.gov/pubmed/21510893 http://dx.doi.org/10.1186/1742-2094-8-38

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