Stem cell biology and drug discovery

There are many reasons to be interested in stem cells, one of the most prominent being their potential use in finding better drugs to treat human disease. This article focuses on how this may be implemented. Recent advances in the production of reprogrammed adult cells and their regulated differenti...

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Detalles Bibliográficos
Autores principales: Rubin, Lee L, Haston, Kelly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110139/
https://www.ncbi.nlm.nih.gov/pubmed/21649940
http://dx.doi.org/10.1186/1741-7007-9-42
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author Rubin, Lee L
Haston, Kelly M
author_facet Rubin, Lee L
Haston, Kelly M
author_sort Rubin, Lee L
collection PubMed
description There are many reasons to be interested in stem cells, one of the most prominent being their potential use in finding better drugs to treat human disease. This article focuses on how this may be implemented. Recent advances in the production of reprogrammed adult cells and their regulated differentiation to disease-relevant cells are presented, and diseases that have been modeled using these methods are discussed. Remaining difficulties are highlighted, as are new therapeutic insights that have emerged.
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spelling pubmed-31101392011-06-08 Stem cell biology and drug discovery Rubin, Lee L Haston, Kelly M BMC Biol Review There are many reasons to be interested in stem cells, one of the most prominent being their potential use in finding better drugs to treat human disease. This article focuses on how this may be implemented. Recent advances in the production of reprogrammed adult cells and their regulated differentiation to disease-relevant cells are presented, and diseases that have been modeled using these methods are discussed. Remaining difficulties are highlighted, as are new therapeutic insights that have emerged. BioMed Central 2011-06-07 /pmc/articles/PMC3110139/ /pubmed/21649940 http://dx.doi.org/10.1186/1741-7007-9-42 Text en Copyright ©2011 Rubin and Haston; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Rubin, Lee L
Haston, Kelly M
Stem cell biology and drug discovery
title Stem cell biology and drug discovery
title_full Stem cell biology and drug discovery
title_fullStr Stem cell biology and drug discovery
title_full_unstemmed Stem cell biology and drug discovery
title_short Stem cell biology and drug discovery
title_sort stem cell biology and drug discovery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110139/
https://www.ncbi.nlm.nih.gov/pubmed/21649940
http://dx.doi.org/10.1186/1741-7007-9-42
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