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Antidepressant Drugs Transactivate TrkB Neurotrophin Receptors in the Adult Rodent Brain Independently of BDNF and Monoamine Transporter Blockade

BACKGROUND: Antidepressant drugs (ADs) have been shown to activate BDNF (brain-derived neurotrophic factor) receptor TrkB in the rodent brain but the mechanism underlying this phenomenon remains unclear. ADs act as monoamine reuptake inhibitors and after prolonged treatments regulate brain bdnf mRNA...

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Detalles Bibliográficos
Autores principales:	Rantamäki, Tomi, Vesa, Liisa, Antila, Hanna, Di Lieto, Antonio, Tammela, Päivi, Schmitt, Angelika, Lesch, Klaus-Peter, Rios, Maribel, Castrén, Eero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110188/ https://www.ncbi.nlm.nih.gov/pubmed/21666748 http://dx.doi.org/10.1371/journal.pone.0020567

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