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Immunogenicity and Efficacy of Flagellin-Fused Vaccine Candidates Targeting 2009 Pandemic H1N1 Influenza in Mice

We have previously demonstrated that the globular head of the hemagglutinin (HA) antigen fused to flagellin of Salmonella typhimurium fljB (STF2, a TLR5 ligand) elicits protective immunity to H1N1 and H5N1 lethal influenza infections in mice (Song et al., 2008, PLoS ONE 3, e2257; Song et al., 2009,...

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Detalles Bibliográficos
Autores principales: Liu, Ge, Tarbet, Bart, Song, Langzhou, Reiserova, Lucia, Weaver, Bruce, Chen, Yan, Li, Hong, Hou, Fu, Liu, Xiangyu, Parent, Jason, Umlauf, Scott, Shaw, Alan, Tussey, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110246/
https://www.ncbi.nlm.nih.gov/pubmed/21687743
http://dx.doi.org/10.1371/journal.pone.0020928