The HLA-B*3906 allele imparts a high risk of diabetes only on specific HLA-DR/DQ haplotypes

AIMS/HYPOTHESIS: We investigated the risk associated with HLA-B*39 alleles in the context of specific HLA-DR/DQ haplotypes. METHODS: We studied a readily available dataset from the Type 1 Diabetes Genetics Consortium that consists of 2,300 affected sibling pair families genotyped for both HLA allele...

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Detalles Bibliográficos
Autores principales: Baschal, E. E., Baker, P. R., Eyring, K. R., Siebert, J. C., Jasinski, J. M., Eisenbarth, G. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110277/
https://www.ncbi.nlm.nih.gov/pubmed/21533899
http://dx.doi.org/10.1007/s00125-011-2161-1

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