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Orange Juice and Its Component, Hesperidin, Decrease the Expression of Multidrug Resistance-Associated Protein 2 in Rat Small Intestine and Liver

We investigated the effects of orange juice (OJ) or hesperidin, a component of OJ, on the pharmacokinetics of pravastatin (PRV) and the expression of both protein and mRNA of multidrug resistance-associated protein 2 (Mrp2) in the rat small intestine and liver. Eight-week-old male Sprague-Dawley rat...

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Detalles Bibliográficos
Autores principales:	Watanabe, Minoru, Matsumoto, Naoki, Takeba, Yuko, Kumai, Toshio, Tanaka, Masami, Tatsunami, Shinobu, Takenoshita-Nakaya, Sachiko, Harimoto, Yoshie, Kinoshita, Yuichi, Kobayashi, Shinichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110312/ https://www.ncbi.nlm.nih.gov/pubmed/21660137 http://dx.doi.org/10.1155/2011/502057

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