Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

BACKGROUND: Down syndrome (DS; trisomy 21) is the most common genetic cause of mental retardation in the human population and key molecular networks dysregulated in DS are still unknown. Many different experimental techniques have been applied to analyse the effects of dosage imbalance at the molecu...

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Detalles Bibliográficos
Autores principales: Vilardell, Mireia, Rasche, Axel, Thormann, Anja, Maschke-Dutz, Elisabeth, Pérez-Jurado, Luis A, Lehrach, Hans, Herwig, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110572/
https://www.ncbi.nlm.nih.gov/pubmed/21569303
http://dx.doi.org/10.1186/1471-2164-12-229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110572/
https://www.ncbi.nlm.nih.gov/pubmed/21569303
http://dx.doi.org/10.1186/1471-2164-12-229

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