Cargando…

Aerosolized BC-819 Inhibits Primary but Not Secondary Lung Cancer Growth

Despite numerous efforts, drug based treatments for patients suffering from lung cancer remains poor. As a promising alternative, we investigated the therapeutic potential of BC-819 for the treatment of lung cancer in mouse tumor models. BC-819 is a novel plasmid DNA which encodes for the A-fragment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hasenpusch, Günther, Pfeifer, Corinna, Aneja, Manish Kumar, Wagner, Kai, Reinhardt, Dietrich, Gilon, Michal, Ohana, Patricia, Hochberg, Avraham, Rudolph, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110766/ https://www.ncbi.nlm.nih.gov/pubmed/21687669 http://dx.doi.org/10.1371/journal.pone.0020760

Ejemplares similares

A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer
por: Lavie, Ofer, et al.
Publicado: (2017)

Synthesis of the 8,19‐Epoxysteroid Eurysterol A
por: Taspinar, Ömer, et al.
Publicado: (2020)

H19-Promoter-Targeted Therapy Combined with Gemcitabine in the Treatment of Pancreatic Cancer
por: Sorin, Vladimir, et al.
Publicado: (2012)

819. Experience with Isavuconazole Use for Treatment of Invasive Fungal Infections
por: Gow-Lee, Vanessa, et al.
Publicado: (2023)

The Increasing Complexity of the Oncofetal H19 Gene Locus: Functional Dissection and Therapeutic Intervention
por: Matouk, Imad, et al.
Publicado: (2013)

The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decision
por: Matouk, Imad J., et al.
Publicado: (2015)

The IL-10 -819T polymorphism is associated with increased susceptibility to severe sepsis
por: Wood, KA, et al.
Publicado: (2003)

Interleukin-10-819 promoter polymorphism in association with gastric cancer risk
por: Xue, Huiping, et al.
Publicado: (2012)

The association of interleukin-10 -1082, -819, -592 polymorphisms and tuberculosis risk
por: Liu, Qianqian, et al.
Publicado: (2015)

HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819
por: Vauthier, Virginie, et al.
Publicado: (2022)

Ice nucleation ability of ammonium sulfate aerosol particles internally mixed with secondary organics
por: Bertozzi, Barbara, et al.
Publicado: (2021)

The non-coding RNAs of the H19-IGF2 imprinted loci: A focus on biological roles and therapeutic potential in Lung Cancer
por: Matouk, Imad J, et al.
Publicado: (2015)

The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory
por: Raveh, Eli, et al.
Publicado: (2015)

Measurement of neutron-proton charge exchange scattering at 8,19 and 24 GeV/c
por: Ellis, Jonathan Richard, et al.
Publicado: (1971)

A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819
por: Fernandes, Liane P., et al.
Publicado: (2022)

Association between interleukin-10-819T/C polymorphism and risk of ischemic stroke: A meta-analysis
por: Zuo, Shuang, et al.
Publicado: (2020)

Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA
por: Schrom, Eva, et al.
Publicado: (2017)

The CTLA4 -819 C/T and +49 A/G dimorphisms are associated with Type 1 diabetes in Egyptian children
por: Saleh, Hatem Mohamed, et al.
Publicado: (2008)

Assessment of prevalence of Anxiety in adult population and development of anxiety scale: A study of 819 patients with anxiety disorder
por: Bano, Zaqia, et al.
Publicado: (2021)

Association of IL-10 -819C/T, -592A/C polymorphisms with the risk of preeclampsia: An updated meta-analysis
por: Che, Guanglu, et al.
Publicado: (2021)

Systematic analysis of the varied designs of 819 therapeutic antibodies and Fc fusion proteins assigned international nonproprietary names
por: Wilkinson, Ian, et al.
Publicado: (2022)

Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life
por: Trepotec, Zeljka, et al.
Publicado: (2019)

CCN concentrations and BC warming influenced by maritime ship emitted aerosol plumes over southern Bay of Bengal
por: Ramana, M. V., et al.
Publicado: (2016)

Interleukin 10 (− 1082 G/A) and (− 819 C/T) gene polymorphisms in Egyptian women with polycystic ovary syndrome (PCOS)
por: Talaat, Roba M., et al.
Publicado: (2016)

Gaps between actual initial treatment of anaphylaxis in China and international guidelines: A review and analysis of 819 reported cases
por: Jiang, Chunyan, et al.
Publicado: (2019)

819. How effective is alcohol flush and drying cycle of automatic endoscope reprocessor (AER): Stripped Endoscope (SE) model
por: Yassin, Mohamed, et al.
Publicado: (2020)

Effects of TNF-α and IL-10-819 T>C single nucleotide polymorphisms on urogenital schistosomiasis in preschool children in Zimbabwe
por: Marume, Amos, et al.
Publicado: (2021)

The pathway of impacts of aerosol direct effects on secondary inorganic aerosol formation
por: Wang, Jiandong, et al.
Publicado: (2022)

Bacterial Cellulose (BC) and BC Composites: Production and Properties
por: Volova, Tatiana G., et al.
Publicado: (2022)

Identification of target genes for spermatogenic cell-specific KRAB transcription factor ZFP819 in a male germ cell line
por: Jin, Sora, et al.
Publicado: (2017)

Relationship Between Interleukin-10 Gene C-819T Polymorphism and Gastric Cancer Risk: Insights From a Meta-Analysis
por: Cui, Xigang, et al.
Publicado: (2016)

Association of Interleukin 10 (IL-10) Gene Polymorphism (819T > C) with Susceptibility to Acute Myeloid Leukemia: A Meta-Analysis
por: Ahadi, Hamid Reza, et al.
Publicado: (2022)

Synthesis, Structure, and Spectroscopy of the Biscarboranyl Stannylenes (bc)Sn·THF and K(2)[(bc)Sn](2) (bc = 1,1′(ortho-Biscarborane)) and Dibiscarboranyl Ethene (bc)CH=CH(bc)
por: Phung, Alice C., et al.
Publicado: (2023)

The Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer
por: Atahan, Kemal, et al.
Publicado: (2011)

Large contribution to secondary organic aerosol from isoprene cloud chemistry
por: Lamkaddam, Houssni, et al.
Publicado: (2021)

Correction to “Synthesis, Structure, and Spectroscopy of the Biscarboranyl Stannylenes (bc)Sn·THF and K(2)[(bc)Sn](2) (bc = 1,1′(ortho-Biscarborane)) and Dibiscarboranyl Ethene (bc)CH=CH(bc)”
por: Phung, Alice C., et al.
Publicado: (2023)

Association of IL10 -819C>T and -592C>A Polymorphisms with Non-Hodgkin Lymphoma Susceptibility: Evidence from Published Studies
por: Zhang, Ting, et al.
Publicado: (2015)

Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature
por: Eason, Ashley C., et al.
Publicado: (2019)

Observation of viscosity transition in α-pinene secondary organic aerosol
por: Järvinen, Emma, et al.
Publicado: (2016)

The peroxins BcPex8, BcPex10, and BcPex12 are required for the development and pathogenicity of Botrytis cinerea
por: Li, Ling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uhsbvgpp1ibv38t1mkdfgjlq0t