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Macrophage-Mediated Optic Neuritis Induced by Retrograde Axonal Transport of Spike Gene Recombinant Mouse Hepatitis Virus

After intracranial inoculation, neurovirulent mouse hepatitis virus (MHV) strains induce acute inflammation, demyelination, and axonal loss in the central nervous system. Prior studies using recombinant MHV strains that differ only in the spike gene, which encodes a glycoprotein involved in virus-ho...

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Detalles Bibliográficos
Autores principales:	Shindler, Kenneth S., Chatterjee, Dhriti, Biswas, Kaushiki, Goyal, Ashish, Dutt, Mahasweta, Nassrallah, Mayssa, Khan, Reas S., Das Sarma, Jayasri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association of Neuropathologists, Inc. 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110774/ https://www.ncbi.nlm.nih.gov/pubmed/21572336 http://dx.doi.org/10.1097/NEN.0b013e31821da499

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