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Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1
Autophagy-dependent mitochondrial turnover in response to cellular stress is necessary for maintaining cellular homeostasis. However, the mechanisms that govern the selective targeting of damaged mitochondria are poorly understood. Parkin, an E3 ubiquitin ligase, has been shown to be essential for t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110820/ https://www.ncbi.nlm.nih.gov/pubmed/21687634 http://dx.doi.org/10.1371/journal.pone.0020975 |