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Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens

BACKGROUND: This study compared the central nervous system (CNS) metastasis incidence between a temozolomide- and a dacarbazine-based regimen in untreated stage IV melanoma patients. METHODS: A total of 150 patients were randomly assigned to receive either oral temozolomide (200 mg m(−2) per day; da...

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Detalles Bibliográficos
Autores principales:	Chiarion-Sileni, V, Guida, M, Ridolfi, L, Romanini, A, Del Bianco, P, Pigozzo, J, Brugnara, S, Colucci, G, Ridolfi, R, De Salvo, G L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111207/ https://www.ncbi.nlm.nih.gov/pubmed/21610711 http://dx.doi.org/10.1038/bjc.2011.178

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