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Thiothymidine combined with UVA as a potential novel therapy for bladder cancer

BACKGROUND: Thiothymidine (S(4)TdR) can be incorporated into DNA and sensitise cells to DNA damage and cell death following exposure to UVA light. Studies were performed to determine if the combination of S(4)TdR and UVA could be an effective treatment for bladder cancer. METHODS: Uptake and incorpo...

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Detalles Bibliográficos
Autores principales: Pridgeon, S W, Heer, R, Taylor, G A, Newell, D R, O'Toole, K, Robinson, M, Xu, Y-Z, Karran, P, Boddy, A V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111209/
https://www.ncbi.nlm.nih.gov/pubmed/21610703
http://dx.doi.org/10.1038/bjc.2011.180