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Update in the methodology of the chronic stress paradigm: internal control matters
To date, the reliability of induction of a depressive-like state using chronic stress models is confronted by many methodological limitations. We believe that the modifications to the stress paradigm in mice proposed herein allow some of these limitations to be overcome. Here, we discuss a variant o...
Autores principales: | Strekalova, Tatyana, Couch, Yvonne, Kholod, Natalia, Boyks, Marco, Malin, Dmitry, Leprince, Pierre, Steinbusch, Harry MW |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111355/ https://www.ncbi.nlm.nih.gov/pubmed/21524310 http://dx.doi.org/10.1186/1744-9081-7-9 |
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