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Genetic variation in TIMP1 but not MMPs predict excess FEV(1 )decline in two general population-based cohorts

BACKGROUND: An imbalance in Matrix MetalloProteases (MMPs) and Tissue Inhibitors of MMPs (TIMPs) contributes to Chronic Obstructive Pulmonary Disease (COPD) development. Longitudinal studies investigating Single Nucleotide Polymorphisms (SNPs) in MMPs and TIMPs with respect to COPD development and l...

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Detalles Bibliográficos
Autores principales:	van Diemen, CC, Postma, DS, Siedlinski, M, Blokstra, A, Smit, HA, Boezen, HM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111362/ https://www.ncbi.nlm.nih.gov/pubmed/21524282 http://dx.doi.org/10.1186/1465-9921-12-57

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