The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

BACKGROUND: Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. RESULTS: We s...

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Detalles Bibliográficos
Autores principales: Prentice, Leah M, d'Anglemont de Tassigny, Xavier, McKinney, Steven, Ruiz de Algara, Teresa, Yap, Damian, Turashvili, Gulisa, Poon, Steven, Sutcliffe, Margaret, Allard, Pat, Burleigh, Angela, Fee, John, Huntsman, David G, Colledge, William H, Aparicio, Samuel AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111392/
https://www.ncbi.nlm.nih.gov/pubmed/21527035
http://dx.doi.org/10.1186/1471-2164-12-209

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