Small Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Cancer Cells

Alternative splicing involves differential exon selection of a gene transcript to generate mRNA and protein isoforms with structural and functional diversity. Abnormal alternative splicing has been shown to be associated with malignant phenotypes of cancer cells, such as chemo-resistance and invasiv...

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Detalles Bibliográficos
Autores principales: Chang, Jan-Gowth, Yang, Den-Mei, Chang, Wen-Hsin, Chow, Lu-Ping, Chan, Wen-Ling, Lin, Hui-Hua, Huang, Hsien-Da, Chang, Ya-Sian, Hung, Cheng-Hao, Yang, Wen-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111415/
https://www.ncbi.nlm.nih.gov/pubmed/21694768
http://dx.doi.org/10.1371/journal.pone.0018643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111415/
https://www.ncbi.nlm.nih.gov/pubmed/21694768
http://dx.doi.org/10.1371/journal.pone.0018643

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