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Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Despite the fact that epithelial ovarian cancers are the leading cause of death from gynecological cancer, very little is known about the pathophysiology of the disease. Mutations in the WNT and PI3K pathways are frequently observed in the human ovarian endometrioid adenocarcinomas (OEAs). However,...

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Detalles Bibliográficos
Autores principales: Tanwar, Pradeep S., Zhang, LiHua, Kaneko-Tarui, Tomoko, Curley, Michael D., Taketo, Makoto M., Rani, Poonam, Roberts, Drucilla J., Teixeira, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111436/
https://www.ncbi.nlm.nih.gov/pubmed/21695255
http://dx.doi.org/10.1371/journal.pone.0020715

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