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Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN
Despite the fact that epithelial ovarian cancers are the leading cause of death from gynecological cancer, very little is known about the pathophysiology of the disease. Mutations in the WNT and PI3K pathways are frequently observed in the human ovarian endometrioid adenocarcinomas (OEAs). However,...
Autores principales: | Tanwar, Pradeep S., Zhang, LiHua, Kaneko-Tarui, Tomoko, Curley, Michael D., Taketo, Makoto M., Rani, Poonam, Roberts, Drucilla J., Teixeira, Jose M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111436/ https://www.ncbi.nlm.nih.gov/pubmed/21695255 http://dx.doi.org/10.1371/journal.pone.0020715 |
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