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Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

BACKGROUND: Phosphoinositide 3-kinase (PI3K)/Akt pathway is linked to the development of asthma. Anti-malarial drug artesunate is a semi-synthetic derivative of artemisinin, the principal active component of a medicinal plant Artemisia annua, and has been shown to inhibit PI3K/Akt activity. We hypot...

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Detalles Bibliográficos
Autores principales:	Cheng, Chang, Ho, W. Eugene, Goh, Fera Y., Guan, Shou Ping, Kong, Li Ren, Lai, Wen-Qi, Leung, Bernard P., Wong, W. S. Fred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111464/ https://www.ncbi.nlm.nih.gov/pubmed/21695271 http://dx.doi.org/10.1371/journal.pone.0020932

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