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Trastuzumab in the Adjuvant Treatment of HER2-Positive Early Breast Cancer Patients: A Meta-Analysis of Published Randomized Controlled Trials

BACKGROUND: Adjuvant trastuzumab therapy has yielded conflicting results for overall survival, concerns about central nervous system (CNS) metastasis, and questions about optimal schedule. Therefore, we carried out a meta-analysis to assess the benefits of concurrent or sequential trastuzumab with a...

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Detalles Bibliográficos
Autores principales: Yin, Wenjin, Jiang, Yiwei, Shen, Zhenzhou, Shao, Zhimin, Lu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111470/
https://www.ncbi.nlm.nih.gov/pubmed/21695277
http://dx.doi.org/10.1371/journal.pone.0021030