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Characterization of 9-Nitrocamptothecin Liposomes: Anticancer Properties and Mechanisms on Hepatocellular Carcinoma In Vitro and In Vivo

BACKGROUND: Hepatocellular carcinoma (HCC) is the third most common cause of cancer related mortality worldwide. 9-Nitrocamptothecin (9NC) is a potent topoisomerase-I inhibitor with strong anticancer effect. To increase the solubility and stability, we synthesized a novel 9NC loaded liposomes (9NC-L...

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Detalles Bibliográficos
Autores principales:	Zheng, Shunzhen, Chang, Shuang, Lu, Jinli, Chen, Zhihui, Xie, Li, Nie, Yu, He, Bin, Zou, Shengquan, Gu, Zhongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111480/ https://www.ncbi.nlm.nih.gov/pubmed/21695227 http://dx.doi.org/10.1371/journal.pone.0021064

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